Serial entrepreneur Frank Addante knew everything at his latest venture, the Rubicon Project, must scale from the very start.
On one day Cyrus Massoumi went door-to-door hawking ZocDoc, the doctor-appointment scheduling site, security guards kicked him out.
GoodData founder Roman Stanek explains what happened when he started to seek financing on September 15, 2008, the same day Lehman Brothers collapsed.
When Yelp launched in 2004, Jeremy Stoppelman and his co-founder thought they were super geniuses. But the site flopped.
Earlier this year, John Borthwick's Betaworks acquired the lagging social news website Digg. Here he talks about how Digg became a start-up again.
Inventor Ray Kurzweil talks about how he created the first print-to-speech reading machine so blind people would use it. Also an author, Kurzweil's most recent book, How to Create a Mind, was published in November.
If not for Australia's then Prime Minister, and an open approach to sponsors, photographer Rick Smolan may not have started the $100 million photo book series.
Atavist CEO and editor Evan Ratliff explains how Atavist navigated the early years.
After buying Excel Dryer, entrepreneur Denis Gagnon realized he had to build a better product. The company spent three years (and almost went bankrupt) creating this new product that would save the company.
The same guy who created Channel One and Philadelphia's Edison Schools has a new obsession: a global private school he calls Avenues.
Steve Hindy wanted to avoid corrupt business dealings. But he was tested as construction wrapped up on his Brooklyn Brewery.
Peter Shapiro negotiated for two years to land the lease to the Port Chester, New York-theater famous for Grateful Dead, Janis Joplin and Pink Floyd concerts.
To sustain a business, Shutterstock CEO Jon Oringer had to balance his price for photos with his payment to photographers.
Stephen McDonnell took a tiny smokehouse and turned it into a $200 million meat company.
How Paul English motivates the programmers at his Kayak.com travel site to respond to customer complaints.
In 2010, OMGPOP had a million loyal users playing games on its website. But it had to go after Facebook to make a huge hit.
Last year, hackers took down music distribution site SoundCloud for 36 hours. Co-founder Alex Ljung explains how SoundCloud responded to millions of infuriated users.
"Saint Jack" picked a fight with an industry--and created a mutual fund powerhouse.
When his father, Ken Lerer, sold The Huffington Post, Ben Lerer realized it's not all about the exit.
Cindy Gallop, founder of MakeLoveNotPorn, explains how every obstacle she encounters only proves why she must launch her "real-world" sex sites.