Businesses Only a Woman Could Start

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Sara Blakely, Spanx

After getting frustrated with unsightly panty lines and uncomfortable undies, Blakely decided to launch her own line of lingerie and shape-wear. The Atlanta-based company launched in 2000, and Spanx has since become a household name. Blakely's undie-innovation has landed her in the spotlight more than once, from the Oprah Winfrey Show to Saturday Night Live. She also recently launched Giving Women a Leg Up, a program that aims to help female entrepreneurs get ahead.