The Entrepreneurs of the Decade: 2000 to 2009

Courtesy Whole Foods
5 of 17

John Mackey of Whole Foods

Following a series of strategic acquisitions in the 1990s, Mackey led his supermarket chain back to a strategy of—wait for it—organic growth, opening 145 stores worldwide between 2000 and 2009. Critics may complain that the company has strayed far from its wholesome roots but, without Whole Foods, it's hard to imagine many of the decades trends in food, from sustainable fishing to artisanal cheese, taking off as they have. And even as the recession has tightened consumers' budgets, Mackey has led the company to steady revenue growth while avoiding layoffs. So what if he sometimes likes to post things on the Internet?