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They've got something to prove.
"When there are doubters, you work a little harder," says Jake Cohen, Detroit Venture Partners' Vice President. "Just the other day, I was on the phone with someone from Sequoia Capital and he was telling me which industries were attracting money on the West Coast--like somehow I wouldn't already know. I think a lot of us have a chip on our shoulder here. People think that our start-ups aren't real, and that we don't know what it's like anywhere else--they think we just got stuck here. But there are a lot of people here who could be anywhere else. It's a choice."