Best Spa for Businessmen: Truefitt & Hill's

Reminiscent of the days when "clubs" served as a home away from home for businessmen, Truefitt & Hill's original London location, which opened in 1805, boasts Charles Dickens and Winston Churchill as past clients. Today, customers have tea and biscuits along with their shoeshines ($6) and hot-lather shaves ($65) to rejuvenate after a long flight or a day of back-to-back meetings.
Chicago, London, and Toronto.
Local Address: 900 North Michigan Avenue
Phone: 312.337.2525

Best Alternative to the Hotel Treadmill: Westin Hotels Guided Running Tours

Many runners will tell you that one of the best things about the sport is the fact that it's free. Thankfully, someone at Westin Hotels seems to agree; the company's hotels in 30 cities employ a "running concierge" who leads guests on three-mile runs three mornings a week, free of charge. Now there's no excuse not to break free from the hotel treadmill.
Local Address: 320 North Dearborn
Phone: 877.866.9216

Best Caffeine Jolt: Intelligentsia Coffee and Tea

Intelligentsia Coffee brews individual servings through a drip right in front of you, so you know you're never getting a bottom-of-the-pot cup. The chain has five spacious, uncluttered coffee bars in Chicago and Los Angeles, where weary travelers can enjoy pick-me-ups such as the Iced Angeleno, four shots of Black Cat espresso shaken with ice, agave nectar and milk. The coffee is sourced directly from growers committed to healthy environmental practices and sustainable social practices. Fans can even sign up for a tour of Intelligentsia's Roasting Works in Chicago.
Local Address: Broadway Coffeebar, 3123 N. Broadway St.; Millenium Park Coffeebar, 53 E. Randolph St.; Monadnock Coffeebar, 53 W. Jackson Blvd.; Chicago Roasting Works, 1850 W. Fulton St.
Phone: 312.563.0023

Best Flight to Asia: United Airlines Chicago to Hong Kong

First class too pricey? United Airlines is spiffing up its international business class with 180-degree lie-flat beds and 15.4-inch widescreen video monitors with access to 150 hours of on-demand movies and TV shows. On select flights, you can connect your iPod and iPhone to the monitors to play movies from iTunes.
Recent price:
$4,400 roundtrip.

Check out the entire 2010 Business Travel 50 list.