It's been a really rough year for MakerBot.

For the second time in 2015, the company is laying off 20 percent of its staff. The downsizing marks a significant shift for the once-hot 3-D printing company, which was acquired by 3-D printing giant Stratasys in mid-2013.

In a blog post, MakerBot's current CEO, Jonathan Jaglom, admitted things haven't been going swimmingly: "For the last few quarters, we did not meet our ambitious goals and we have to make significant changes to ensure MakerBot's future growth and success." He intones that there's an upside to cutting back the staff, and trimming the headquarters back to just one building in Industry City, a block of warehouses in Brooklyn that have been transformed to artists' studios and startup digs. Just MakerBot's actual factory will remain in Industry City; other employees will be located in the company's more corporate-feeling Downtown Brooklyn location. "In order to lead our dynamic industry, we need to get back to our entrepreneurial spirit and address our fractured organizational structure," he wrote.

Elsewhere, Jaglom blamed "dynamics of the market" for the missed goals. And that may be true: 3-D printing is nowhere near as buzzy as it was two years ago, when MakerBot was acquired.

MakerBot is looking to become more nimble, and with that is also shifting manufacturing strategies, turning to contract manufacturers to produce the older, fourth-generation of MakerBot printers--which means the remaining factory at Industry City will only produce its current product line (including the Replicator Mini, the Replicator, and the Replicator Z18). Though Jaglom made clear the Brooklyn factory, which employs 140 people and spans 170,000 feet, isn't going anywhere, the layoffs reportedly span all departments. At last check more than a year ago, MakerBot had 500 employees. This last round of layoffs, after a previous 20 percent cut in April, means the company is down to slightly more than 300.

The market for MakerBot seems to have shifted over the past year, away from its core market of consumers, and into the educational space. That shift is clearly a challenge.

But MakerBot has a bigger challenge: It's no longer a scrappy, entrepreneur-run company. Bre Pettis, the charming founder--and something of a Mr. Rogers of the maker community--appeared to step away from MakerBot mid-2014, to run a project within Stratasys called Bold Machines. This July, it was discovered that Bold Machines was being spun out of the company entirely.

So MakerBot today is subject to the goals set by Stratasys, which is having its own market struggles this year. And from the inside, MakerBot likely feels like a very, very different place than it did two years ago, when it was acting like a scrappy, albeit fast-growing, startup. It'll be no breeze for Jaglom to recapture that feeling.