Katrina Lake tested the business model from her Cambridge, Massachusetts, apartment, sending boxes of clothes tailored to her clients’ tastes. Five years later, the San Francisco-based company has more than 5,000 employees and a plus-size service on the way.

Co-founded by Charles Jolley and Mike Hanson, Ozlo is a virtual personal assistant. Available since October, after running a six-month private beta test, Ozlo receives data from more than 30 partners, including Yelp and Wikipedia.

Co-founders J.P. Montúfar and John Tabis cut the middlemen out of the flower industry. Bouqs' “farm-to-user” model gives it an edge price-wise, but the real bloom is in its wedding services. Just ask Shark Tank’s Robert Herjavec.

Former BuzzFeed executive Jon Steinberg launched his Millennial-driven, video-streaming news site Cheddar last April. The NYC-based startup has raised more than $10 million in funding and boasts partnerships with Vimeo, Twitter, and Amazon Video.

The internet’s first GIF search engine just closed a $72 million Series D round at an estimated $600 million valuation. Founded in 2013 by Alex Chung (top left) and Jace Cook, the company has become core to messaging apps from Outlook to Tinder.

Emily Weiss, founder of makeup and skin care brand Glossier, can flaunt product waiting lists of more than 10,000 clients. She has amassed a cult following, fueled by her already successful beauty blog Into the Gloss.

Created by former Buddhist monk Andy Puddicombe (pictured) and Rich Pierson, the app teaches meditation to more than nine million people in 190 countries. Famous users include actor Jared Leto, who is also an investor.

The creators of Twitter (including Evan Williams, pictured) have brought you Medium, a blogging platform with over 25 million monthly users. Its new publisher feature allows businesses to host their websites' blogs. On its client list? Cheddar and Ozlo.

The Millennial media website was created by Chris Altchek and Jake Horowitz in 2011. It reached 12.1 million U.S. unique visitors last October, according to Comscore.

The Shanghai-based startup is taking the music industry by storm. Founded by Luyu Yang and Alex Zhu in 2014, the app now boasts over 140 million users worldwide who record short videos of themselves lip-syncing and dancing to popular songs.

Miki Agrawal (pictured), along with twin sister Radha and friend Antonia Saint Dunbar, launched "period panties" in 2014. Two years later, Thinx is making serious waves in the $15 billion feminine care products industry.

Co-founded by Bastian Lehmann in 2011, the food-delivery business serves 44 U.S. markets and says it completes over a million deliveries from 56,000 merchants each month. Last October, it closed a $141 million investment round.

Swedish entrepreneurs Per Cromwell, Maria De La Croix, and Tomas Mazetti started their café bicycle (see it here) business in 2015. It already has 700 clients in 68 countries. The startup says it doubles in size every six months.

Founded by filmmaker Chris Milk and technologist Aaron Koblin, this startup focuses on creating story-driven virtual reality content. Among its clients are The New York Times, Vice Media, NBC, and the United Nations.

Led by Tien Tzuo, the California-based company offers a commerce platform solution for businesses in the subscription economy. Ford, Dell, DocuSign, and British newspaper The Guardian are clients.