It's not every day that Bill Gates asks you for help. Well, a couple days ago, he did just that. In a tweet, Gates invited all of us to take on 10 big global challenges that the world needs our help to solve.

The 10 big global challenges that Bill Gates pointed to were listed in a recent issue of MIT Technology Review. These challenges are no joke. But solving them (or even just one or two) will be an incredibly important step forward for humanity -- and for our planet.

The 10 challenges include:

  • Carbon sequestration (removing carbon dioxide from the atmosphere and storing it safely away)
  • Grid-scale energy storage (cheaper and more efficient ways to store vast amounts of energy produced by renewable sources such as wind and solar)
  • Universal flu vaccine (a vaccine that works for all forms of flu, including the less harmful variants as well as the catastrophic ones)
  • Dementia treatment (Alzheimer's and other forms of dementia remain poorly understood)
  • Ocean clean-up (billions of tiny pieces of plastic -- "microplastics" -- are floating in the world's oceans)
  • Energy-efficient desalination (as the world's population grows, the need to turn salt water into fresh water also increases)
  • Safe driverless car (progress is being made, but there's a long way to go)
  • Embodied AI (AI that has the ability to interact with the physical world like people and animals do)
  • Earthquake prediction (a few hours' warning of a coming earthquake could save millions of lives)
  • Brain decoding (cracking the code of how the brain works could lead to all sorts of breakthroughs)

As Bill Gates once said, "We always overestimate the change that will occur in the next two years and underestimate the change that will occur in the next 10. Don't let yourself be lulled into inaction."

It's up to us to be the change we want to see.