A media agency for nonprofits, Media Cause inherently impacts local communities. It has educated 870 million people on issues dear to its clients and recruited 334,000 new members to their online communities, according to the company's first annual report, published in 2020. Media Cause's work on Tap Cancer Out helped raise more than $870,000 for childhood cancer research, while the firm helped more than 4,500 low-income families enroll their children in free charter schools in New York and Boston.

Culture Shift Labs revolves around financial and economic inclusion for the Black community and achieving visible results in racial equality. Its annual summit, Culture Shifting Weekends, is dedicated to providing opportunities to Black executives, venture investors, entrepreneurs, and nonprofit leaders. For the past 17 years, the summit has helped facilitate more than $350 million in deals and collaborations for attendees. Culture Shift's goal is to get $1 billion into the hands of this community by 2025.

The convergence of Covid-19 and the Black Lives Matter movement presented a unique opportunity to Mentor Spaces, a virtual mentorship platform for Black and Latinx early-career professionals. Mentor Space’s mission is to make all workplaces diverse, equitable, and inclusive while advancing and maximizing the careers of underrepresented talent by providing a platform for professionals to have their own voice. The app already has more than 10,000 active students, helping them recognize their strengths, values, and interests to confidently reach their goals.

Waste from electronics, or e-waste, is the world’s fastest-growing solid waste stream. To help ensure that the products we need are built sustainably, top brands need to get smarter and more efficient throughout the entire design-build process. This year, Instrumental introduced an A.I.-powered discovery system along with external data streams to enable engineers to find flaws as they occur and amend them before they create vast quantities of waste.

Bloodstream infections are extremely dangerous, but positive blood tests are wrong roughly a third of the time. Kurin severely reduces the risk of blood-test contamination and benefits patients by providing the correct care for their correct diagnosis, saving hospitals time and money by excluding unnecesary treatments and medication. In 2019, Hartford Hospital published a peer-reviewed paper demonstrating a 74 percent reduction in their contaminated cultures by implementing Kurin, leading to an estimated annual savings of $750,000.